This study focused on the challenges of at-scale corequisite mathematics course development and implementation based on the experiences of 21 system leaders, college administrators, and faculty across four states. Corequisite courses allow students who need or want additional support in college-level math to enroll in credit-bearing courses to receive extra, just-in-time help. Based on the identified challenges, this study also illuminated enabling conditions and provides recommendations for policymakers, state and college leaders, and campus faculty as they engage in corequisite development and implementation.